SOCS5 抗体 (AA 1-270)
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北京 101111
Quick Overview for SOCS5 抗体 (AA 1-270) (ABIN7171006)
抗原
See all SOCS5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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原理
- SOCS5 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Suppressor of cytokine signaling 5 protein (1-270AA)
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 5 (SOCS5) (N-Term) antibody
SOCS5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-140) antibodySOCS5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-110) antibodySOCS5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-270) antibodySOCS5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) antibodySOCS5 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-536) antibodySOCS5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-536) antibodySOCS5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
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别名
- SOCS5
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背景
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.
Aliases: SOCS5 antibody, CIS6 antibody, CISH5 antibody, CISH6 antibody, KIAA0671Suppressor of cytokine signaling 5 antibody, SOCS-5 antibody, Cytokine-inducible SH2 protein 6 antibody, CIS-6 antibody, Cytokine-inducible SH2-containing protein 5 antibody
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UniProt
- O75159
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
抗原
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