SRPK2 抗体 (AA 471-688)
Quick Overview for SRPK2 抗体 (AA 471-688) (ABIN7170677)
抗原
See all SRPK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-688
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human SRSF protein kinase 2 protein (471-688AA)
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亚型
- IgG
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anti-SFRS Protein Kinase 2 (SRPK2) (AA 1-699) antibody
SRPK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) antibodySRPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 420-520) antibodySRPK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 380-617) antibodySRPK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 465-495), (C-Term) antibodySRPK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3353 unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SRPK2 (SFRS Protein Kinase 2 (SRPK2))
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别名
- SRPK2
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背景
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Background: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.
Aliases: Human serine kinase SRPK2 mRNA, complete cds antibody, Serine kinase SRPK2 antibody, Serine/arginine rich protein specific kinase 2 antibody, Serine/arginine-rich protein-specific kinase 2 antibody, Serine/threonine protein kinase SRPK2 antibody, SFRS protein kinase 2 antibody, SFRSK2 antibody, SR protein specific kinase 2 antibody, SR-protein-specific kinase 2 antibody, SRPK2 antibody, SRPK2_HUMAN antibody, SRSF protein kinase 2 C-terminal antibody
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UniProt
- P78362
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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