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- 抗原 See all SRPK2 抗体
- SRPK2 (SFRS Protein Kinase 2 (SRPK2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRPK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- SRPK2 Antibody detects endogenous levels of total SRPK2
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SRPK2
- 亚型
- IgG
- Top Product
- Discover our top product SRPK2 Primary Antibody
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anti-SFRS Protein Kinase 2 (SRPK2) (AA 471-688) antibody
SRPK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 1-699) antibodySRPK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) antibodySRPK2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 420-520) antibodySRPK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 380-617) antibodySRPK2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-SFRS Protein Kinase 2 (SRPK2) (AA 465-495), (C-Term) antibodySRPK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3353 unconjugated
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- 应用备注
- WB 1:1000-3000 IHC 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- SRPK2 (SFRS Protein Kinase 2 (SRPK2))
- 别名
- SRPK2 (SRPK2 产品)
- 别名
- SFRSK2 antibody, AW226533 antibody, AW492537 antibody, AW547358 antibody, Wbp6 antibody, mSRPK2 antibody, sfrsk2 antibody, srpk2 antibody, srpk2-b antibody, srpk2b antibody, SRSF protein kinase 2 antibody, serine/arginine-rich protein specific kinase 2 antibody, SRSF protein kinase 2 L homeolog antibody, SRPK2 antibody, Srpk2 antibody, srpk2 antibody, srpk2.L antibody
- 背景
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Description: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.
Gene: SRPK2
- 分子量
- 78 kDa
- 基因ID
- 6733
- UniProt
- P78362
- 途径
- Ribonucleoprotein Complex Subunit Organization
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