电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SRPK2 抗体 (AA 471-688)

SRPK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7170677
发货至: 中国
  • 抗原 See all SRPK2 抗体
    SRPK2 (SFRS Protein Kinase 2 (SRPK2))
    抗原表位
    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 471-688
    适用
    • 44
    • 32
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 2
    克隆类型
    • 44
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SRPK2 antibody is un-conjugated
    应用范围
    • 17
    • 15
    • 14
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human SRSF protein kinase 2 protein (471-688AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SRPK2 (SFRS Protein Kinase 2 (SRPK2))
    别名
    SRPK2 (SRPK2 产品)
    别名
    SFRSK2 antibody, AW226533 antibody, AW492537 antibody, AW547358 antibody, Wbp6 antibody, mSRPK2 antibody, sfrsk2 antibody, srpk2 antibody, srpk2-b antibody, srpk2b antibody, SRSF protein kinase 2 antibody, serine/arginine-rich protein specific kinase 2 antibody, SRSF protein kinase 2 L homeolog antibody, SRPK2 antibody, Srpk2 antibody, srpk2 antibody, srpk2.L antibody
    背景

    Background: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.

    Aliases: Human serine kinase SRPK2 mRNA, complete cds antibody, Serine kinase SRPK2 antibody, Serine/arginine rich protein specific kinase 2 antibody, Serine/arginine-rich protein-specific kinase 2 antibody, Serine/threonine protein kinase SRPK2 antibody, SFRS protein kinase 2 antibody, SFRSK2 antibody, SR protein specific kinase 2 antibody, SR-protein-specific kinase 2 antibody, SRPK2 antibody, SRPK2_HUMAN antibody, SRSF protein kinase 2 C-terminal antibody

    UniProt
    P78362
    途径
    Ribonucleoprotein Complex Subunit Organization
You are here: