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Shugoshin 抗体 (AA 260-439) (FITC)

This anti-Shugoshin antibody is a 兔 多克隆 antibody detecting Shugoshin in . Suitable for 人.
产品编号 ABIN7169547
发货至: 中国

Quick Overview for Shugoshin 抗体 (AA 260-439) (FITC) (ABIN7169547)

抗原

See all Shugoshin (SGOL1) 抗体
Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))

适用

  • 39
  • 5
  • 5
  • 1
  • 1
  • 1

宿主

  • 38
  • 3

克隆类型

  • 39
  • 2
多克隆

标记

  • 27
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Shugoshin antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-439

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Shugoshin 1 protein (260-439AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))

    别名

    SGO1

    背景

    Background: Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.

    Aliases: hSgo 1 antibody, hSgo1 antibody, NY BR 85 antibody, Serologically defined breast cancer antigen NY BR 85 antibody, Serologically defined breast cancer antigen NY-BR-85 antibody, SGO 1 antibody, SGO antibody, SGO L1 antibody, SGO1 antibody, SGOL 1 antibody, SGOL1 antibody, SGOL1_HUMAN antibody, Shugoshin 1AB protein antibody, Shugoshin 1CD protein antibody, Shugoshin 1EFprotein antibody, Shugoshin 1GH protein antibody, Shugoshin 1KL protein antibody, Shugoshin like 1 (S. pombe) antibody, Shugoshin like 1 antibody, Shugoshin-like 1 antibody

    UniProt

    Q5FBB7

    途径

    Maintenance of Protein Location
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