SRRT 抗体 (AA 627-876)
Quick Overview for SRRT 抗体 (AA 627-876) (ABIN7169355)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 627-876
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Serrate RNA effector molecule homolog protein (627-876AA)
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亚型
- IgG
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anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 1-796) antibody
SRRT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (C-Term) antibodyVerified SRRT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 733-766) antibodySRRT 适用: 人, 斑马鱼 WB 宿主: 兔 Polyclonal RB53167 unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 878-910) antibodySRRT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53166 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- SRRT
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背景
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Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
Aliases: ARS2 protein antibody, Arsenate resistance protein ARS2 antibody, Arsenite resistance protein 2 antibody, Arsenite resistance protein antibody, Arsenite-resistance protein 2 antibody, ASR2 antibody, MGC126427 antibody, Serrate antibody, Serrate RNA effector molecule antibody, Serrate RNA effector molecule homolog (Arabidopsis) antibody, Serrate RNA effector molecule homolog antibody, SRRT antibody, SRRT_HUMAN antibody
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UniProt
- Q9BXP5
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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