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VRK1 抗体 (AA 257-396)

This anti-VRK1 antibody is a 兔 多克隆 antibody detecting VRK1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7169217
发货至: 中国
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Quick Overview for VRK1 抗体 (AA 257-396) (ABIN7169217)

抗原

See all VRK1 抗体
VRK1 (Vaccinia Related Kinase 1 (VRK1))

适用

  • 49
  • 11
  • 3

宿主

  • 41
  • 8

克隆类型

  • 43
  • 6
多克隆

标记

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  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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This VRK1 antibody is un-conjugated

应用范围

  • 41
  • 15
  • 13
  • 13
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 257-396

    原理

    VRK1 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Serine/threonine-protein kinase VRK1 protein (257-396AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    别名

    VRK1

    背景

    Background: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates \\\'Thr-18\\\' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

    Aliases: MGC117401 antibody, MGC138280 antibody, MGC142070 antibody, PCH1 antibody, PCH1A antibody, Serine/threonine protein kinase VRK1 antibody, Serine/threonine-protein kinase VRK1 antibody, Vaccinia related kinase 1 antibody, Vaccinia virus B1R related kinase 1 antibody, Vaccinia-related kinase 1 antibody, VRK1 antibody, VRK1_HUMAN antibody

    UniProt

    Q99986
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