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VRK1 抗体 (C-Term)

VRK1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044560
发货至: 中国
  • 抗原 See all VRK1 抗体
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    抗原表位
    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 292-329, C-Term
    适用
    • 41
    • 11
    • 3
    人, 大鼠
    宿主
    • 34
    • 7
    克隆类型
    • 36
    • 5
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VRK1 antibody is un-conjugated
    应用范围
    • 39
    • 15
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase VRK1(VRK1) detection. Tested with WB in Human,Rat.
    序列
    EKNKPGEIAK YMETVKLLDY TEKPLYENLR DILLQGLK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase VRK1(VRK1) detection. Tested with WB in Human,Rat.
    Gene Name: vaccinia related kinase 1
    Protein Name: Serine/threonine-protein kinase VRK1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1 (292-329aa EKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLK), different from the related mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product VRK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    别名
    VRK1 (VRK1 产品)
    别名
    vrk1 antibody, MGC64390 antibody, MGC75762 antibody, VRK1 antibody, PCH1 antibody, PCH1A antibody, 51PK antibody, wu:fe16f06 antibody, zgc:56266 antibody, vaccinia related kinase 1 L homeolog antibody, vaccinia related kinase 1 antibody, Serine/threonine-protein kinase VRK1 antibody, vrk1.L antibody, vrk1 antibody, VRK1 antibody, vrk-1 antibody, Vrk1 antibody
    背景
    Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    Synonyms: MGC117401 antibody|MGC138280 antibody|MGC142070 antibody|PCH1 antibody|PCH1A antibody|Serine/threonine protein kinase VRK1 antibody| Serine/threonine-protein kinase VRK1 antibody|Vaccinia related kinase 1 antibody|Vaccinia virus B1R related kinase 1 antibody| Vaccinia-related kinase 1 antibody|VRK1 antibody|VRK1_HUMAN antibody
    基因ID
    7443
    UniProt
    Q99986
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