ULK2 抗体 (AA 211-276) (Biotin)
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北京 101111
Quick Overview for ULK2 抗体 (AA 211-276) (Biotin) (ABIN7169210)
抗原
See all ULK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 211-276
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原理
- ULK2 Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Serine/threonine-protein kinase ULK2 protein (211-276AA)
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亚型
- IgG
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anti-Unc-51 Like Kinase 2 (ULK2) (C-Term) antibody
ULK2 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 1-155) antibodyULK2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2H4B2 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 211-276) antibodyULK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (Internal Region) antibodyULK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) antibodyULK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ULK2 (Unc-51 Like Kinase 2 (ULK2))
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别名
- ULK2
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背景
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Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR, however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.
Aliases: ATG1B antibody, KIAA0623 antibody, Serine/threonine protein kinase ULK2 antibody, Serine/threonine-protein kinase ULK2 antibody, ULK2 antibody, ULK2_HUMAN antibody, Unc 51 (C. elegans) like kinase 2 antibody, Unc 51 like autophagy activating kinase 2 antibody, Unc 51 like kinase 2 antibody, Unc-51-like kinase 2 antibody, Unc51.2 antibody
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UniProt
- Q8IYT8
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途径
- Regulation of Cell Size, Autophagy
抗原
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