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PINK1 抗体 (AA 162-272)

This anti-PINK1 antibody is a 兔 多克隆 antibody detecting PINK1 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7169153
发货至: 中国

Quick Overview for PINK1 抗体 (AA 162-272) (ABIN7169153)

抗原

See all PINK1 抗体
PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PINK1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 162-272

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

    别名

    PINK1

    背景

    Background: Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at \\\'Ser-65\\\' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291).

    Aliases: BRPK antibody, FLJ27236 antibody, mitochondrial antibody, PARK 6 antibody, PARK6 antibody, Phosphatase and Tensin Homolog antibody, PINK 1 antibody, PINK1 antibody, PINK1_HUMAN antibody, Protein kinase BRPK antibody, PTEN induced putative kinase 1 antibody, PTEN induced putative kinase protein 1 antibody, PTEN-induced putative kinase protein 1 antibody, Serine/threonine kinase PINK1 mitochondrial antibody, Serine/threonine protein kinase PINK1 mitochondrial antibody, Serine/threonine-protein kinase PINK1 antibody

    UniProt

    Q9BXM7

    途径

    Autophagy
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