PAK3 抗体 (AA 70-190)
Quick Overview for PAK3 抗体 (AA 70-190) (ABIN7169128)
抗原
See all PAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-190
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)
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亚型
- IgG
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anti-PAK3 (PAK3) (AA 1-90) antibody
PAK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4G8F11 unconjugated
anti-PAK3 (PAK3) (AA 124-152) antibodyPAK3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-PAK3 (PAK3) (Ser154) antibodyPAK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 124-152), (N-Term) antibodyPAK3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34657 unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PAK3
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别名
- PAK3
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背景
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Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody
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UniProt
- O75914
抗原
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