UPF3B 抗体 (AA 319-423)
Quick Overview for UPF3B 抗体 (AA 319-423) (ABIN7167644)
抗原
See all UPF3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 319-423
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Regulator of nonsense transcripts 3B protein (319-423AA)
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亚型
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 416-452), (C-Term) antibody
UPF3B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) antibodyUPF3B 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (N-Term) antibodyUPF3B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 252-301) antibodyUPF3B 适用: 人, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 1-180) antibodyUPF3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
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别名
- UPF3B
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背景
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Background: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core.
Aliases: UPF3B antibody, RENT3B antibody, UPF3X antibody, Regulator of nonsense transcripts 3B antibody, Nonsense mRNA reducing factor 3B antibody, Up-frameshift suppressor 3 homolog B antibody, hUpf3B antibody, Up-frameshift suppressor 3 homolog on chromosome X antibody, hUpf3p-X antibody
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UniProt
- Q9BZI7
抗原
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