MAS1 抗体 (AA 246-325)
Quick Overview for MAS1 抗体 (AA 246-325) (ABIN7166484)
抗原
See all MAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 246-325
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Proto-oncogene Mas protein (246-325AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAS1 (MAS1 Oncogene (MAS1))
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别名
- MAS1
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背景
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Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Aliases: MAS antibody, MAS proto oncogene antibody, Mas-related G protein-coupled receptor A antibody, MAS_HUMAN antibody, Mas1 antibody, MAS1 oncogene antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MGRA antibody, Proto-oncogene Mas antibody
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UniProt
- P04201
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途径
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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