PTBP1 抗体 (AA 135-292)
Quick Overview for PTBP1 抗体 (AA 135-292) (ABIN7163887)
抗原
See all PTBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-292
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Polypyrimidine tract-binding protein 1 protein (135-292AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
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别名
- PTBP1
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背景
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Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Aliases: 57 kDa RNA binding protein PPTB 1 antibody, 57 kDa RNA-binding protein PPTB-1 antibody, Heterogeneous nuclear ribonucleoprotein I antibody, Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody, hnRNP I antibody, HNRNP-I antibody, HNRNPI antibody, HNRPI antibody, MGC10830 antibody, MGC8461 antibody, Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody, Polypyrimidine Tract Binding Protein 1 antibody, Polypyrimidine tract binding protein antibody, Polypyrimidine tract-binding protein 1 antibody, pPTB antibody, PTB 1 antibody, PTB 2 antibody, PTB 3 antibody, PTB 4 antibody, PTB antibody, PTB T antibody, PTB1 antibody, PTB2 antibody, PTB3 antibody, PTB4 antibody, PTBP 1 antibody, PTBP1 antibody, PTBP1_HUMAN antibody, PTBT antibody, RNA Binding Protein antibody
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UniProt
- P26599
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途径
- Regulation of Muscle Cell Differentiation
抗原
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