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BMI1 抗体 (AA 1-247) (Biotin)

This anti-BMI1 antibody is a 兔 多克隆 antibody detecting BMI1 in ELISA. Suitable for 人.
产品编号 ABIN7163791
发货至: 中国

Quick Overview for BMI1 抗体 (AA 1-247) (Biotin) (ABIN7163791)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

适用

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宿主

  • 78
  • 58
  • 6

克隆类型

  • 78
  • 64
多克隆

标记

  • 87
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This BMI1 antibody is conjugated to Biotin

应用范围

  • 109
  • 74
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  • 4
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ELISA
  • 抗原表位

    • 38
    • 9
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    AA 1-247

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Polycomb complex protein BMI-1 protein (1-247AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    BMI1

    背景

    Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373). The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed:21772249, PubMed:25355358). In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:26151332, PubMed:21772249).

    Aliases: B lymphoma Mo MLV insertion region (mouse) antibody, B lymphoma Mo MLV insertion region 1 homolog antibody, Bmi 1 antibody, BMI1 antibody, BMI1 polycomb ring finger oncogene antibody, BMI1_HUMAN antibody, Flvi 2/bmi 1 antibody, FLVI2/BMI1 antibody, MGC12685 antibody, Murine leukemia viral (bmi 1) oncogene homolog antibody, Oncogene BMI 1 antibody, PCGF 4 antibody, PCGF4 antibody, Polycomb complex protein BMI 1 antibody, Polycomb complex protein BMI-1 antibody, Polycomb group protein Bmi1 antibody, Polycomb group ring finger 4 antibody, Polycomb group RING finger protein 4 antibody, RING finger protein 51 antibody, RNF 51 antibody, RNF51 antibody

    UniProt

    P35226

    途径

    Cell Division Cycle, Autophagy
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