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PODXL 抗体 (AA 32-458) (FITC)

This anti-PODXL antibody is a 兔 多克隆 antibody detecting PODXL in . Suitable for 人.
产品编号 ABIN7163726
发货至: 中国

Quick Overview for PODXL 抗体 (AA 32-458) (FITC) (ABIN7163726)

抗原

See all PODXL 抗体
PODXL (Podocalyxin-Like (PODXL))

适用

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宿主

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克隆类型

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多克隆

标记

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This PODXL antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 32-458

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Podocalyxin protein (32-458AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PODXL (Podocalyxin-Like (PODXL))

    别名

    PODXL

    背景

    Background: Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

    Aliases: GCTM-2 antigen antibody, Gp2 antibody, Gp200 antibody, MGC138240 antibody, PC antibody, PCLP antibody, PCLP-1 antibody, PCLP1 antibody, Pcx antibody, Podocalyxin antibody, Podocalyxin like antibody, Podocalyxin like protein antibody, Podocalyxin-like protein 1 antibody, Podxl antibody, PODXL_HUMAN antibody

    UniProt

    O00592

    途径

    Tube Formation
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