PODXL 抗体 (AA 32-458) (Biotin)
Quick Overview for PODXL 抗体 (AA 32-458) (Biotin) (ABIN7163725)
抗原
See all PODXL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-458
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Podocalyxin protein (32-458AA)
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亚型
- IgG
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anti-Podocalyxin-Like (PODXL) antibody
PODXL 适用: 人 WB, IHC, ELISA, IP, FACS, IF 宿主: 小鼠 Monoclonal 4D2G7 unconjugated
anti-Podocalyxin-Like (PODXL) (Extracellular Domain) antibodyPODXL 适用: 人, 大鼠, 兔 WB, IHC, IP, FACS, IF, StM 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 32-458) antibodyPODXL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) antibodyPODXL 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5F5 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 220-431) antibodyPODXL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 171-404) antibodyPODXL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 310-447) antibodyPODXL 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PODXL-2185 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 451-558) antibodyPODXL 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 153-386) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 408-485) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- PODXL
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背景
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Background: Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Aliases: GCTM-2 antigen antibody, Gp2 antibody, Gp200 antibody, MGC138240 antibody, PC antibody, PCLP antibody, PCLP-1 antibody, PCLP1 antibody, Pcx antibody, Podocalyxin antibody, Podocalyxin like antibody, Podocalyxin like protein antibody, Podocalyxin-like protein 1 antibody, Podxl antibody, PODXL_HUMAN antibody
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UniProt
- O00592
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途径
- Tube Formation
抗原
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