PAI1 抗体 (AA 24-398) (HRP)
Quick Overview for PAI1 抗体 (AA 24-398) (HRP) (ABIN7163535)
抗原
See all PAI1 (SERPINE1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-398
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Plasminogen activator inhibitor 1 protein (24-398AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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别名
- SERPINE1
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背景
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Background: Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed:9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed:18386027). It is involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084).
Aliases: Clade E antibody, Endothelial plasminogen activator inhibitor antibody, Nexin antibody, Nexin plasminogen activator inhibitor type 1 antibody, PAI 1 antibody, PAI antibody, PAI-1 antibody, PAI1_HUMAN antibody, PLANH1 antibody, Plasminogen activator inhibitor 1 antibody, Plasminogen activator inhibitor type 1 antibody, Serine (or cysteine) proteinase inhibitor antibody, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody, Serine proteinase inhibitor clade E member 1 antibody, serpin antibody, Serpin E1 antibody, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody, Serpin peptidase inhibitor clade E antibody, Serpine 1 antibody, SERPINE1 antibody
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UniProt
- P05121
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途径
- p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
抗原
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