PPARG 抗体 (AA 1-477) (Biotin)
Quick Overview for PPARG 抗体 (AA 1-477) (Biotin) (ABIN7163014)
抗原
See all PPARG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-477
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Peroxisome proliferator-activated receptor gamma protein (1-477AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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别名
- PPARG
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背景
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Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
Aliases: CIMT1 antibody, GLM1 antibody, NR1C3 antibody, Nuclear receptor subfamily 1 group C member 3 antibody, OTTHUMP00000185032 antibody, OTTHUMP00000185036 antibody, Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody, Peroxisome proliferator activated receptor gamma 1 antibody, Peroxisome Proliferator Activated Receptor gamma antibody, Peroxisome proliferator-activated receptor gamma antibody, PPAR gamma antibody, PPAR-gamma antibody, PPARG antibody, PPARG_HUMAN antibody, PPARG1 antibody, PPARG2 antibody, PPARgamma antibody
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UniProt
- P37231
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途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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