MACROD1 抗体 (AA 83-325) (FITC)
Quick Overview for MACROD1 抗体 (AA 83-325) (FITC) (ABIN7162105)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 83-325
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
-
亚型
- IgG
-
-
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-325) antibody
MACROD1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibodyMACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (N-Term) antibodyMACROD1 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
-
别名
- MACROD1
-
背景
-
Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody
-
UniProt
- Q9BQ69
抗原
-
