MACROD1 抗体 (N-Term)
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北京 101111
Quick Overview for MACROD1 抗体 (N-Term) (ABIN2791083)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MACROD1 Antibody - N-terminal region
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序列
- MAAKVDLSTS TDWKEAKSFL KGLSDKQREE HYFCKDFVRL KKIPTWKEMA
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预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MACROD1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1
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anti-MACRO Domain Containing 1 (MACROD1) (AA 83-325) antibody
MACROD1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibodyMACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68610-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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别名
- MACROD1
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背景
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Background Information: MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.
Alternative Symbols: LRP16
Protein Name: O-acetyl-ADP-ribose deacetylase MACROD1
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分子量
- 36kDa
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基因ID
- 28992
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NCBI登录号
- NP_054786
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UniProt
- Q9BQ69
抗原
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