-
- 抗原 See all MACROD1 products
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
-
抗原表位
- AA 83-325
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MACROD1 antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
- 亚型
- IgG
-
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibody
MACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (N-Term) antibodyMACROD1 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- MACROD1 (MACRO Domain Containing 1 (MACROD1))
- 别名
- MACROD1 (MACROD1 产品)
- 别名
- lrp16 antibody, d930010j01rik antibody, LRP16 antibody, AI604841 antibody, AW743046 antibody, D930010J01Rik antibody, Lrp16 antibody, MACRO domain containing 1 antibody, MACRO domain containing 1 L homeolog antibody, MACROD1 antibody, macrod1 antibody, macrod1.L antibody, Macrod1 antibody
- 背景
-
Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody
- UniProt
- Q9BQ69
-
You are here:
