MACROD1 抗体 (AA 83-325) (Biotin)
Quick Overview for MACROD1 抗体 (AA 83-325) (Biotin) (ABIN7162104)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-325
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
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亚型
- IgG
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anti-MACRO Domain Containing 1 (MACROD1) (AA 83-325) antibody
MACROD1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibodyMACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (N-Term) antibodyMACROD1 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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别名
- MACROD1
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背景
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Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Aliases: MACROD1 antibody, LRP16 antibody, ADP-ribose glycohydrolase MACROD1 antibody, MACRO domain-containing protein 1 antibody, O-acetyl-ADP-ribose deacetylase MACROD1 antibody, EC 3.1.1.106 antibody, Protein LRP16 antibody, [Protein ADP-ribosylaspartate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody, [Protein ADP-ribosylglutamate] hydrolase MACROD1 antibody, EC 3.2.2.- antibody
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UniProt
- Q9BQ69
抗原
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