COBRA1 抗体 (AA 8-199) (Biotin)
Quick Overview for COBRA1 抗体 (AA 8-199) (Biotin) (ABIN7161140)
抗原
See all COBRA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-199
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Negative elongation factor B protein (8-199AA)
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亚型
- IgG
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anti-Cofactor of BRCA1 (COBRA1) (Center) antibody
COBRA1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 8-199) antibodyCOBRA1 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- COBRA1 (Cofactor of BRCA1 (COBRA1))
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别名
- NELFB
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背景
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Background: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. Binds RNA which may help to stabilize the NELF complex on nucleic acid. In vitro, binds weakly to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1. May be able to induce chromatin unfolding.
Aliases: NELFB antibody, COBRA1 antibody, KIAA1182 antibody, Negative elongation factor B antibody, NELF-B antibody, Cofactor of BRCA1 antibody
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UniProt
- Q8WX92
抗原
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