NAE1 抗体 (Regulatory Subunit)
Quick Overview for NAE1 抗体 (Regulatory Subunit) (ABIN7161137)
抗原
See all NAE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220, Regulatory Subunit
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human NEDD8-activating enzyme E1 regulatory subunit protein (1-220AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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别名
- NAE1
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背景
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Background: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Aliases: 59 kDa antibody, A 116A10.1 antibody, Amyloid beta precursor protein binding protein 1 59kD antibody, Amyloid beta precursor protein binding protein 1 59 kDa antibody, Amyloid beta precursor protein binding protein 1 antibody, Amyloid beta precursor protein binding protein 1, 59 kDa antibody, Amyloid beta precursor protein-binding protein 1 antibody, Amyloid protein binding protein 1 antibody, Amyloid protein-binding protein 1 antibody, APP BP1 antibody, APP-BP1 antibody, APPBP 1 antibody, APPBP1 antibody, HPP 1 antibody, HPP1 antibody, NAE 1 antibody, NAE1 antibody, NEDD8 activating enzyme E1 regulatory subunit antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, Proto oncogene protein 1 antibody, Proto-oncogene protein 1 antibody, Protooncogene protein 1 antibody, ula 1 antibody, ULA1_HUMAN antibody
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UniProt
- Q13564
抗原
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