SETD8 抗体 (AA 136-258) (Biotin)
Quick Overview for SETD8 抗体 (AA 136-258) (Biotin) (ABIN7160767)
抗原
See all SETD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-258
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human N-lysine methyltransferase KMT5A protein (136-258AA)
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亚型
- IgG
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anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 109-272) antibody
SETD8 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5E10F7 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 109-272) antibodySETD8 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 7H1G10 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 73-352) antibodySETD8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 220-249) antibodySETD8 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18964 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 136-258) antibodySETD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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别名
- KMT5A
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背景
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Background: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates \\\'Lys-20\\\' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration.
Aliases: H4 K20 HMTase antibody, H4 K20 specific histone methyltransferase antibody, H4-K20-HMTase SETD8 antibody, Histone H4 K20 methyltransferase antibody, Histone lysine N methyltransferase H4 lysine 20 specific antibody, Histone-lysine N-methyltransferase SETD8 antibody, Lysine N-methyltransferase 5A antibody, N-lysine methyltransferase SETD8 antibody, Pr SET 7 antibody, Pr SET7 antibody, PR-Set7 antibody, PR/SET domain containing protein 07 antibody, PR/SET domain containing protein 8 antibody, PR/SET domain-containing protein 07 antibody, PR/SET07 antibody, PrSET7 antibody, SET 07 antibody, SET 8 antibody, SET domain containing (lysine methyltransferase) 8 antibody, SET domain containing 8 antibody, SET domain containing lysine methyltransferase 8 antibody, SET domain containing protein 8 antibody, SET domain-containing protein 8 antibody, SET07 antibody, SET8 antibody, SETD 8 antibody, setd8 antibody, SETD8_HUMAN antibody
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UniProt
- Q9NQR1
抗原
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