MUC1 抗体 (AA 24-273)
Quick Overview for MUC1 抗体 (AA 24-273) (ABIN7160277)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 24-273
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Mucin-1 protein (24-273AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- MUC1 (Mucin 1 (MUC1))
-
别名
- MUC1
-
背景
-
Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. Ref.26 Ref.37 Ref.40 Ref.45 Ref.46 Ref.49 Ref.52 Ref.53 Ref.56.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Aliases: ADMCKD antibody, ADMCKD1 antibody, Breast carcinoma associated antigen DF3 antibody, Breast carcinoma-associated antigen DF3 antibody, CA 15-3 antibody, CA15 3 antibody, CA15 3 antigen antibody, CA15-3 antibody, CA15.3 antibody, Cancer antigen 15-3 antibody, Carcinoma associated mucin antibody, Carcinoma-associated mucin antibody, CD 227 antibody, CD227 antibody, DF3 antigen antibody, EMA antibody, Episialin antibody, Epithelial Membrane Antigen antibody, H23 antigen antibody, H23AG antibody, KL 6 antibody, KL-6 antibody, KL6 antibody, Krebs von den Lungen-6 antibody, MAM 6 antibody, MAM6 antibody, MCD antibody, MCKD antibody, MCKD1 antibody, Medullary cystic kidney disease 1 (autosomal dominant) antibody, Medullary cystic kidney disease, autosomal dominant antibody, MUC 1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1 antibody, MUC1-alpha antibody, MUC1-beta antibody, MUC1-CT antibody, MUC1-NT antibody, MUC1/ZD antibody, MUC1_HUMAN antibody, Mucin 1 antibody, Mucin 1 cell surface associated antibody, Mucin 1 transmembrane antibody, Mucin 1, cell surface associated antibody, Mucin-1 subunit beta antibody, Peanut reactive urinary mucin antibody, Peanut-reactive urinary mucin antibody, PEM antibody, PEMT antibody, Polymorphic epithelial mucin antibody, PUM antibody, Tumor associated epithelial membrane antigen antibody, Tumor associated epithelial mucin antibody, Tumor associated mucin antibody, Tumor-associated epithelial membrane antigen antibody, Tumor-associated mucin antibody
-
UniProt
- P15941
-
途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
-