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MST1R 抗体 (AA 1175-1400)

This anti-MST1R antibody is a 兔 多克隆 antibody detecting MST1R in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7158896
发货至: 中国

Quick Overview for MST1R 抗体 (AA 1175-1400) (ABIN7158896)

抗原

See all MST1R 抗体
MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

适用

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宿主

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克隆类型

  • 99
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多克隆

标记

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This MST1R antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 36
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    AA 1175-1400

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Macrophage-stimulating protein receptor protein (1175-1400AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

    别名

    MST1R

    背景

    Background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.

    Aliases: c met related tyrosine kinase antibody, CD136 antibody, CD136 antigen antibody, CDw136 antibody, Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody, Macrophage stimulating 1 receptor antibody, Macrophage stimulating protein receptor alpha chain antibody, MACROPHAGE STIMULATING PROTEIN RECEPTOR antibody, Macrophage stimulating protein receptor beta chain antibody, Macrophage-Stimulating 1 Receptor (MST1R) antibody, Macrophage-stimulating protein receptor beta chain antibody, MSP receptor antibody, Mst1r antibody, MST1R variant RON30 antibody, MST1R variant RON62 antibody, NPCA3 antibody, p185 RON antibody, p185-Ron antibody, Protein-tyrosine kinase 8 antibody, PTK 8 antibody, ptk8 antibody, PTK8 protein tyrosine kinase 8 antibody, Recepteur drigine nantais (RON) antibody, RON antibody, RON protein tyrosine kinase antibody, RON variant E2E3 antibody, RON_HUMAN antibody, Soluble RON variant 1 antibody, Soluble RON variant 2 antibody, Soluble RON variant 3 antibody, Soluble RON variant 4 antibody, Stem cell derived tyrosine kinase antibody

    UniProt

    Q04912

    途径

    RTK signaling
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