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SHP1 抗体 (pTyr536)

Name: SHP1 抗体 (pTyr536)
SKU: ABIN711626
Availability: OutOfStock

PTPN6 适用: 人, 小鼠 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti phospho-PTPN6(Tyr536) Polyclonal Antibody, Unconjugated (ABIN711626) at 1:200 followed by conjugation to the secondary antibody and DAB staining (SHP1 抗体 (pTyr536))

IHC

Paraformaldehyde-fixed, paraffin embedded human glioma, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with PTPN6(Tyr536) Polyclonal Antibody (bs-5577R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining. (SHP1 抗体 (pTyr536))

IHC (p)

2 images

产品编号 ABIN711626

发货至: 中国

Datasheet as PDF

抗原 See all SHP1 (PTPN6) 抗体

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
抗原表位
34

12

7

7

5

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr536
适用
119

72

55

3

2

2

2

2

1

1

1

1
人, 小鼠
宿主
107

14

1
兔
Compatible Secondaries
克隆类型
95

27
多克隆
标记
60

7

6

5

5

5

5

5

5

3

3

2

2

2

2

2

2

1
This SHP1 antibody is un-conjugated
应用范围
85

34

26

21

20

13

13

12

9

6

4

4

2

2

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠

预测反应

Dog,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human PTPN6 around the phosphorylation site of Tyr536 [SE(p-Y)GN]

亚型

IgG

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anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal CPTC-APEX1-2 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人 WB, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) antibody
PTPN6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 243-541) antibody
PTPN6 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2E9E4 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597), (Isoform 2) antibody
PTPN6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (C-Term) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 100-400) antibody
PTPN6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277) antibody
PTPN6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17225 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

别名

PTPN6 (PTPN6 产品)

别名

HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody

背景

Synonyms: SHP-1Tyr536, PTPN6phospho Y536, SHP1phospho Y536, 70 kda SHP1L protein, HCP, HCPH, Hematopoietic cell phosphatase, Hematopoietic cell protein tyrosine phosphatase, Hematopoietic cell protein-tyrosine phosphatase, HPTP1C, Protein tyrosine phosphatase 1C, Protein tyrosine phosphatase non receptor type 6, Protein tyrosine phosphatase SHP1, PTP1C, PTPN6, SH PTP 1, SHP1, SHP1L, PTN6_HUMAN.
Background: SHP1 is a member of the non receptor protein tyrosine phosphatase subfamily. The PTP family comprises of at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is cytosolic. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. SHP1 is implicated in the control of tyrosine kinase signalling pathways in cellular proliferation, with a potential role in cancer.

基因ID

5777

UniProt

P29350

途径

JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling