IFT57 抗体 (AA 170-429)
Quick Overview for IFT57 抗体 (AA 170-429) (ABIN7156999)
抗原
See all IFT57 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-429
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Intraflagellar transport protein 57 homolog protein (170-429AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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别名
- IFT57
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背景
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Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5\\\'-AAAGACATG-3\\\' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
Aliases: CDNA FLJ10147 fis clone HEMBA1003369 antibody, Dermal papilla derived protein 8 antibody, Dermal papilla-derived protein 8 antibody, DERP 8 antibody, DERP8 antibody, Esrrbl 1 antibody, Esrrbl1 antibody, ESRRBL1 protein antibody, Estrogen related receptor beta like 1 antibody, Estrogen related receptor beta like protein 1 antibody, Estrogen-related receptor beta-like protein 1 antibody, FLJ10147 antibody, Hip1 Interacting protein antibody, HIP1 interacting protein HIPPI antibody, Hip1 protein interactor antibody, HIP1-interacting protein antibody, HIPPI antibody, Huntingtin interacting protein 1 interacting protein antibody, Huntingtin interacting protein 1 protein interactor antibody, IFT 57 antibody, ift57 antibody, IFT57_HUMAN antibody, Intraflagellar transport 57 homolog (Chlamydomonas) antibody, Intraflagellar transport 57 homolog antibody, Intraflagellar transport protein 57 homolog antibody, MHS4R2 antibody, Vestrogen related receptor beta like 1 antibody
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UniProt
- Q9NWB7
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途径
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
抗原
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