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IL1RAP 抗体 (AA 21-356)

This anti-IL1RAP antibody is a 兔 多克隆 antibody detecting IL1RAP in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7156734
发货至: 中国
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Quick Overview for IL1RAP 抗体 (AA 21-356) (ABIN7156734)

抗原

See all IL1RAP 抗体
IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

适用

  • 50
  • 12
  • 4

宿主

  • 42
  • 9
  • 4

克隆类型

  • 32
  • 23
多克隆

标记

  • 32
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This IL1RAP antibody is un-conjugated

应用范围

  • 35
  • 12
  • 11
  • 8
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-356

    原理

    IL1RAP Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Interleukin-1 receptor accessory protein (21-356AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

    别名

    IL1RAP

    背景

    Background: Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

    Aliases: C3orf13 antibody, FLJ37788 antibody, IL 1 receptor accessory protein antibody, IL 1R 3 antibody, IL 1R3 antibody, IL 1RAcP antibody, IL 1RAP antibody, IL-1 receptor accessory protein antibody, IL-1R-3 antibody, IL-1R3 antibody, IL-1RAcP antibody, IL-1RAP antibody, IL1 receptor accessory protein antibody, IL1AP_HUMAN antibody, IL1R3 antibody, IL1RAcP antibody, Il1rap antibody, Interleukin 1 Accessory Protein antibody, interleukin 1 receptor 3 antibody, Interleukin 1 receptor accessory protein antibody, interleukin 1 receptor accessory protein beta antibody, Interleukin-1 receptor 3 antibody, Interleukin-1 receptor accessory protein antibody

    UniProt

    Q9NPH3

    途径

    NF-kappaB Signaling, Growth Factor Binding
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