Integrin beta 2 抗体 (AA 37-201)
Quick Overview for Integrin beta 2 抗体 (AA 37-201) (ABIN7156481)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-201
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Integrin beta-2 protein (37-201AA)
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亚型
- IgG
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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 适用: 人 FACS, WB, IP, IHC (fro), Func, IHC (p) 宿主: 小鼠 Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 适用: 人 FACS, WB, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibody (Biotin)ITGB2 适用: 人 FACS, WB, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal MEM-48 Biotin
anti-Integrin beta 2 (ITGB2) antibody (FITC)ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-48 FITC
anti-Integrin beta 2 (ITGB2) antibody (PE)ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-48 PE
anti-Integrin beta 2 (ITGB2) (AA 70-170) antibodyITGB2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 适用: 小鼠 FACS, WB, IP, IHC (fro), Func, IHC (p) 宿主: 大鼠 Monoclonal M18-2 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 559-700) antibodyITGB2 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3C11G5 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 17-382) antibodyITGB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) (AA 701-770) antibodyITGB2 适用: 人, 大鼠 ELISA, IHC (fro), ICC, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Integrin beta 2 (ITGB2)
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别名
- ITGB2
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背景
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Background: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
Aliases: 95 subunit beta antibody, Beta 2 (antigen CD18 (p95) antibody, CD 18 antibody, CD18 antibody, Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody, Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody, Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody, Complement component 3 receptor 3 and 4 subunit antibody, Complement receptor C3 beta subunit antibody, Complement receptor C3 subunit beta antibody, Integrin beta 2 antibody, Integrin beta chain beta 2 antibody, Integrin beta-2 (ITGB2) antibody, Integrin beta-2 antibody, Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody, ITB2_HUMAN antibody, ITGB2 antibody, LAD antibody, LCAMB antibody, Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody, Leukocyte cell adhesion molecule CD18 antibody, LFA 1 antibody, LFA1 antibody, Lymphocyte function associated antigen 1 (LFA1) antibody, Lymphocyte function associated antigen 1 antibody, MAC 1 antibody, MAC1 antibody, Macrophage antigen 1 (mac1) beta antibody, MF17 antibody, MFI7 antibody, OTTHUMP00000115278 antibody, OTTHUMP00000115279 antibody, OTTHUMP00000115280 antibody, OTTHUMP00000115281 antibody, OTTHUMP00000115282 antibody
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UniProt
- P05107
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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