ITGA5 抗体 (AA 220-472) (Biotin)
Quick Overview for ITGA5 抗体 (AA 220-472) (Biotin) (ABIN7156443)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 220-472
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                                            交叉反应
- 人
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                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human Integrin alpha-5 protein (220-472AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - ITGA5 (Integrin, alpha 5 (ITGA5))
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                                            别名
- ITGA5
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                                            背景
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                        Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). Aliases: CD49 antigen-like family member E antibody, CD49e antibody, Fibronectin receptor subunit alpha antibody, Fibronectin receptor, alpha subunit antibody, FNRA antibody, Integrin alpha 5 (fibronectin receptor alpha) antibody, Integrin alpha-5 antibody, Integrin alpha-5 light chain antibody, Integrin alpha-F antibody, Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody, ITA5_HUMAN antibody, Itga5 antibody, Very late activation protein 5, alpha subunit antibody, VLA-5 antibody, VLA5 antibody, VLA5A antibody 
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                                            UniProt
- P08648
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                                            途径
- Integrin Complex
 抗原
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