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ITGA5 抗体 (AA 220-472)

This anti-ITGA5 antibody is a 兔 多克隆 antibody detecting ITGA5 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7156442
发货至: 中国

Quick Overview for ITGA5 抗体 (AA 220-472) (ABIN7156442)

抗原

See all ITGA5 抗体
ITGA5 (Integrin, alpha 5 (ITGA5))

适用

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宿主

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克隆类型

  • 80
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多克隆

标记

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This ITGA5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    AA 220-472

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Integrin alpha-5 protein (220-472AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ITGA5 (Integrin, alpha 5 (ITGA5))

    别名

    ITGA5

    背景

    Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).

    Aliases: CD49 antigen-like family member E antibody, CD49e antibody, Fibronectin receptor subunit alpha antibody, Fibronectin receptor, alpha subunit antibody, FNRA antibody, Integrin alpha 5 (fibronectin receptor alpha) antibody, Integrin alpha-5 antibody, Integrin alpha-5 light chain antibody, Integrin alpha-F antibody, Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody, ITA5_HUMAN antibody, Itga5 antibody, Very late activation protein 5, alpha subunit antibody, VLA-5 antibody, VLA5 antibody, VLA5A antibody

    UniProt

    P08648

    途径

    Integrin Complex
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