KPNB1 抗体 (AA 9-214)
Quick Overview for KPNB1 抗体 (AA 9-214) (ABIN7156134)
抗原
See all KPNB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-214
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Importin subunit beta-1 protein (9-214AA)
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亚型
- IgG
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anti-Karyopherin (Importin) beta 1 (KPNB1) (C-Term) antibody
Verified KPNB1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 250-350) antibodyKPNB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 190-216), (N-Term) antibodyKPNB1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20681 unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) antibodyKPNB1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 190-216) antibodyKPNB1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 144-193) antibodyKPNB1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (AA 21-441) antibodyKPNB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin (Importin) beta 1 (KPNB1) (N-Term) antibodyKPNB1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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别名
- KPNB1
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背景
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Background: Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In association with IPO7 mediates the nuclear import of H1 histone. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. Imports SNAI1 and PRKCI into the nucleus.
Aliases: IMB 1 antibody, IMB1 antibody, IMB1_HUMAN antibody, Impnb antibody, Importin 90 antibody, Importin beta 1 antibody, Importin beta 1 subunit antibody, Importin subunit beta-1 antibody, Importin-90 antibody, IPOB antibody, Karyopherin beta 1 antibody, Karyopherin beta 1 subunit antibody, Karyopherin subunit beta-1 antibody, KPNB 1 antibody, Kpnb1 antibody, MGC2155 antibody, MGC2156 antibody, MGC2157 antibody, NTF 97 antibody, NTF97 antibody, NTF97/Importin beta antibody, Nuclear factor P97 antibody, Pore targeting complex 97 kDa subunit antibody, PTAC97 antibody
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UniProt
- Q14974
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途径
- Protein targeting to Nucleus
抗原
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