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SETD7 抗体 (AA 1-218) (HRP)

This anti-SETD7 antibody is a 兔 多克隆 antibody detecting SETD7 in ELISA. Suitable for 人.
产品编号 ABIN7155520
发货至: 中国
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Quick Overview for SETD7 抗体 (AA 1-218) (HRP) (ABIN7155520)

抗原

See all SETD7 抗体
SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

适用

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宿主

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克隆类型

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多克隆

标记

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This SETD7 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 1-218

    原理

    SETD7 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-218AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

    别名

    SETD7

    背景

    Background: Histone methyltransferase that specifically monomethylates \\\'Lys-4\\\' of histone H3. H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates \\\'Lys-189\\\' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates \\\'Lys-372\\\' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

    Aliases: FLJ21193 antibody, H3 K4 HMTase antibody, H3-K4-HMTase SETD7 antibody, H4 lysine 4 specific antibody, Histone H3 K4 methyltransferase antibody, Histone H3 lysine 4 specific methyltransferase antibody, Histone H3-K4 methyltransferase SETD7 antibody, Histone H4 K4 methyltransferase antibody, Histone lysine N methyltransferase antibody, Histone lysine N methyltransferase H3 lysine 4 specific SET7 antibody, Histone-lysine N-methyltransferase SETD7 antibody, KIAA1717 antibody, KMT7 antibody, Lysine methyltransferase antibody, Lysine N-methyltransferase 7 antibody, OTTHUMP00000164543 antibody, OTTHUMP00000220049 antibody, SET 7 antibody, SET 7/9 antibody, SET 9 antibody, SET D7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SET domain containing protein 7 antibody, SET domain containing protein 8 antibody, SET domain-containing protein 7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, Setd7 antibody, SETD7_HUMAN antibody

    UniProt

    Q8WTS6
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