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FZD7 抗体 (AA 161-239)

This 兔 多克隆 anti-FZD7 antibody specifically detects FZD7 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7153189
发货至: 中国
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Quick Overview for FZD7 抗体 (AA 161-239) (ABIN7153189)

抗原

See all FZD7 抗体
FZD7 (Frizzled Family Receptor 7 (FZD7))

适用

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宿主

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克隆类型

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多克隆

标记

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This FZD7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 161-239

    原理

    FZD7 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Frizzled-7 protein (161-239AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FZD7 (Frizzled Family Receptor 7 (FZD7))

    别名

    FZD7

    背景

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    Aliases: Frizzled 7, seven transmembrane spanning receptor antibody, frizzled class receptor 7 antibody, Frizzled drosophila homolog of 7 antibody, Frizzled family receptor 7 antibody, Frizzled homolog 7 antibody, Frizzled-7 antibody, Frizzled7 antibody, Fz 7 antibody, Fz-7 antibody, Fz7 antibody, FZD 7 antibody, FZD7 antibody, FZD7_HUMAN antibody, FzE 3 antibody, FzE3 antibody, hFz 7 antibody, hFz7 antibody, Homolog of Drosophila Frizzled 7 antibody, OTTHUMP00000163742 antibody

    UniProt

    O75084

    途径

    WNT signaling, Stem Cell Maintenance
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