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FZD1 抗体 (AA 125-225) (Biotin)

This anti-FZD1 antibody is a 兔 多克隆 antibody detecting FZD1 in ELISA. Suitable for 人.
产品编号 ABIN7153180
发货至: 中国

Quick Overview for FZD1 抗体 (AA 125-225) (Biotin) (ABIN7153180)

抗原

See all FZD1 (Fzd1) 抗体
FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FZD1 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 125-225

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Frizzled-10 protein (125-225AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

    别名

    FZD1

    背景

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    Aliases: CD 350 antibody, CD 350 antigen antibody, CD350 antibody, Frizzled (Drosophila) homolog 10 antibody, Frizzled-10 antibody, FZ 10 antibody, Fz-10 antibody, FZ10 antibody, FZD 10 antibody, FZD10 antibody, FZD10_HUMAN antibody, FzE 7 antibody, FzE7 antibody, hFz 10 antibody, hFz10 antibody

    UniProt

    Q9ULW2

    途径

    WNT signaling, Asymmetric Protein Localization
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