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FZD10 抗体

FZD10 适用: 人, 小鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258746
发货至: 中国
  • 抗原 See all FZD10 抗体
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    适用
    • 40
    • 36
    • 20
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    人, 小鼠, 猴
    宿主
    • 44
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD10 antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 13
    • 13
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    FZD10 antibody detects endogenous levels of total FZD10
    交叉反应
    人, 猴, 小鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide
    亚型
    IgG
    Top Product
    Discover our top product FZD10 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    别名
    FZD10 (FZD10 产品)
    别名
    CD350 antibody, FZ-10 antibody, Fz10 antibody, FzE7 antibody, hFz10 antibody, cFz-10 antibody, Fz-10 antibody, Xfr9 antibody, Xfz10 antibody, frizzled-10 antibody, frizzled10 antibody, fz10 antibody, fze7 antibody, hfz10 antibody, fk48e04 antibody, fz4 antibody, fzb antibody, wu:fk48e04 antibody, zg04 antibody, Xfz10A antibody, fzd10a antibody, Xfz10B antibody, Xfz9 antibody, fzd10b antibody, fzd9 antibody, frizzled class receptor 10 antibody, frizzled class receptor 10 L homeolog antibody, frizzled class receptor 10 S homeolog antibody, FZD10 antibody, fzd10 antibody, Fzd10 antibody, fzd10.L antibody, fzd10.S antibody
    背景

    Description: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).

    Gene: FZD10

    分子量
    65 kDa
    基因ID
    11211
    UniProt
    Q9ULW2
    途径
    WNT signaling
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