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FZD1 抗体 (AA 73-322) (FITC)

This anti-FZD1 antibody is a 兔 多克隆 antibody detecting FZD1 in . Suitable for 人.
产品编号 ABIN7153177
发货至: 中国

Quick Overview for FZD1 抗体 (AA 73-322) (FITC) (ABIN7153177)

抗原

See all FZD1 (Fzd1) 抗体
FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

适用

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宿主

  • 36
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克隆类型

  • 39
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多克隆

标记

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This FZD1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 4
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    AA 73-322

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Frizzled-1 protein (73-322AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

    别名

    FZD1

    背景

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

    Aliases: Chfz-1 antibody, Dfrizzled-1 antibody, DKFZp564G072 antibody, FLJ95923 antibody, Frizzled 1 antibody, Frizzled homolog 1 (Drosophila) antibody, Frizzled homolog 1 antibody, Frizzled-1 antibody, Fz receptor 1 antibody, Fz-1 antibody, Fz1 antibody, FZD1 antibody, FZD1_HUMAN antibody, FzE1 antibody, hFz1 antibody, Rfz1 antibody, Wnt receptor antibody, Xfrizzled-1 antibody

    UniProt

    Q9UP38

    途径

    WNT signaling, Asymmetric Protein Localization
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