FZD1 抗体 (N-Term)
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- 抗原 See all FZD1 (Fzd1) 抗体
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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抗原表位
- N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- FZD1 Antibody detects endogenous levels of total FZD1.
- 预测反应
- Pig,Zebrafish,Bovine
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human FZD1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product Fzd1 Primary Antibody
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anti-Frizzled Family Receptor 1 (Fzd1) (AA 117-322) antibody
Fzd1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 125-225) antibodyFzd1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 73-322) antibodyFzd1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 374-404), (Middle Region) antibodyFzd1 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (N-Term) antibodyFzd1 适用: 人, 小鼠, 大鼠, Hamster, 马, 猴, 兔, Bat, Cow, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 367-396) antibodyFzd1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14325 unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) antibodyFzd1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (N-Term) antibodyFzd1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 1-15) antibodyFzd1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 210-320) antibodyFzd1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- 别名
- FZD1 (Fzd1 产品)
- 别名
- CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody
- 背景
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Description: Receptor for Wnt proteins (PubMed:10557084). Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B (PubMed:10557084). Contradictory results showing activation by WNT7B have been described for mouse (By similarity). Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10557084). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10557084). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
Gene: FZD1
- 分子量
- 71 kDa
- 基因ID
- 8321
- UniProt
- Q9UP38
- 途径
- WNT signaling, Asymmetric Protein Localization
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