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FAK 抗体 (pSer722)

This anti-FAK antibody is a 兔 多克隆 antibody detecting FAK in WB, ELISA, IF (p), IF (cc), IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN711056
发货至: 中国

Quick Overview for FAK 抗体 (pSer722) (ABIN711056)

抗原

See all FAK (PTK2) 抗体
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FAK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer722

    特异性

    Recognizes Ser760 in mice

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Ser722

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    别名

    Fak

    背景

    Synonyms: FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, PTK2

    Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]

    基因ID

    5747

    UniProt

    Q05397

    途径

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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