FADD 抗体 (AA 1-208)
Quick Overview for FADD 抗体 (AA 1-208) (ABIN7152581)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-208
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human FAS-associated death domain protein (1-208AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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别名
- FADD
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背景
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Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Aliases: FADD antibody, FADD protein antibody, FADD_HUMAN antibody, Fas (TNFRSF6) associated via death domain antibody, Fas associated via death domain antibody, Fas associating death domain containing protein antibody, Fas associating protein antibody, Fas associating protein with death domain antibody, Fas TNFRSF6 associated via death domain antibody, FAS-associated death domain protein antibody, FAS-associating death domain-containing protein antibody, GIG 3 antibody, GIG3 antibody, Growth inhibiting gene 3 protein antibody, Growth-inhibiting gene 3 protein antibody, H sapiens mRNA for mediator of receptor induced toxicity antibody, Mediator of receptor induced toxicity antibody, MGC8528 antibody, MORT 1 antibody, MORT1 antibody, Protein FADD antibody
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UniProt
- Q13158
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途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
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