FANCD2 抗体 (AA 1-291)
Quick Overview for FANCD2 抗体 (AA 1-291) (ABIN7152548)
抗原
See all FANCD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-291
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Fanconi anemia group D2 protein (1-291AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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别名
- FANCD2
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背景
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Background: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Aliases: DKFZp762A223 antibody, FA 4 antibody, FA D2 antibody, FA4 antibody, FAC D2 antibody, FACD 2 antibody, FACD antibody, FACD2 antibody, FACD2_HUMAN antibody, FAD antibody, FAD2 antibody, FANC D2 antibody, FANCD 2 antibody, FANCD antibody, FANCD2 antibody, FANCONI ANEMIA COMPLEMENTATION GROUP D antibody, Fanconi anemia complementation group D2 antibody, Fanconi anemia group D2 protein antibody, FANCONI PANCYTOPENIA TYPE 4 antibody, FLJ23826 antibody, OTTHUMP00000158853 antibody, OTTHUMP00000207925 antibody, Protein FACD2 antibody, Type 4 Fanconi pancytopenia antibody
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UniProt
- Q9BXW9
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途径
- DNA Damage Repair
抗原
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