EYA1 抗体 (AA 168-321)
Quick Overview for EYA1 抗体 (AA 168-321) (ABIN7152355)
抗原
See all EYA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 168-321
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Eyes absent homolog 1 protein (168-321AA)
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亚型
- IgG
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anti-Eyes Absent Homolog 1 (EYA1) (AA 100-170) antibody
EYA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (AA 100-250) antibodyEYA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Middle Region) antibodyEYA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Internal Region) antibodyVerified EYA1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (C-Term) antibodyEYA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EYA1 (Eyes Absent Homolog 1 (EYA1))
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别名
- EYA1
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背景
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Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \\\'Tyr-142\\\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \\\'Tyr-142\\\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19234442). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1, it plays an important role in hypaxial muscle development, in this it is functionally redundant with EYA2 (By similarity).
Aliases: BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, Eya1 antibody, EYA1_HUMAN antibody, Eyes absent 1 antibody, Eyes absent 1 homolog antibody, Eyes absent homolog 1 (Drosophila) antibody, Eyes absent homolog 1 antibody, Eyes absent homolog1 antibody, MGC141875 antibody, OFC1 antibody
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UniProt
- Q99502
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途径
- Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
抗原
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