EYA1 抗体 (AA 231-330) (Biotin)
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- 抗原 See all EYA1 抗体
- EYA1 (Eyes Absent Homolog 1 (EYA1))
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抗原表位
- AA 231-330
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EYA1 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EYA1
- 亚型
- IgG
- Top Product
- Discover our top product EYA1 Primary Antibody
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anti-Eyes Absent Homolog 1 (EYA1) (AA 100-170) antibody
EYA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (AA 100-250) antibodyEYA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Middle Region) antibodyEYA1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (AA 168-321) antibodyEYA1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Internal Region) antibodyVerified EYA1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (C-Term) antibodyEYA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- EYA1 (Eyes Absent Homolog 1 (EYA1))
- 别名
- EYA1 (EYA1 产品)
- 别名
- EYA1 antibody, bop antibody, bor antibody, XEya1 antibody, wu:fc13c10 antibody, zgc:100770 antibody, BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, EYA transcriptional coactivator and phosphatase 1 L homeolog antibody, EYA1 antibody, eya1 antibody, Eya1 antibody, eya1.L antibody
- 背景
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Synonyms: BOP, BOR, BOS1, OFC1, Eyes absent homolog 1, EYA1
Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears. Together with SIX1, it plays an important role in hypaxial muscle development, in this it is functionally redundant with EYA2.
- 基因ID
- 2138
- UniProt
- Q99502
- 途径
- Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
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