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EPH Receptor A2 抗体 (AA 627-976) (FITC)

This 兔 多克隆 antibody specifically detects EPH Receptor A2 . It exhibits reactivity toward 人.
产品编号 ABIN7151837
发货至: 中国
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Quick Overview for EPH Receptor A2 抗体 (AA 627-976) (FITC) (ABIN7151837)

抗原

See all EPH Receptor A2 (EPHA2) 抗体
EPH Receptor A2 (EPHA2)

适用

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宿主

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克隆类型

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多克隆

标记

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This EPH Receptor A2 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 627-976

    原理

    EPHA2 Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ephrin type-A receptor 2 protein (627-976AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EPH Receptor A2 (EPHA2)

    别名

    EPHA2

    背景

    Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

    Aliases: ARCC2 antibody, AW545284 antibody, CTPA antibody, CTPP1 antibody, CTRCT6 antibody, EC 2.7.10.1 antibody, Eck antibody, Eph receptor A2 antibody, EPHA2 antibody, EPHA2_HUMAN antibody, Ephrin receptor antibody, Ephrin receptor EphA2 antibody, Ephrin type A receptor 2 antibody, Ephrin type-A receptor 2 antibody, Epithelial cell kinase antibody, Epithelial cell receptor protein tyrosine kinase antibody, Myk 2 antibody, Myk2 antibody, Sek 2 antibody, Sek2 antibody, Soluble EPHA2 variant 1 antibody, Tyrosine protein kinase receptor ECK antibody, Tyrosine-protein kinase receptor ECK antibody, Tyrosine-protein kinase receptor MPK-5 antibody, Tyrosine-protein kinase receptor SEK-2 antibody

    UniProt

    P29317

    途径

    RTK signaling
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