ZNRF3 抗体 (AA 56-219)
Quick Overview for ZNRF3 抗体 (AA 56-219) (ABIN7151318)
抗原
See all ZNRF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-219
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)
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亚型
- IgG
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anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 120-165) antibody
ZNRF3 适用: 人, 小鼠, 大鼠 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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别名
- ZNRF3
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背景
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Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Aliases: ZNRF3 antibody, KIAA1133 antibody, RNF203 antibody, E3 ubiquitin-protein ligase ZNRF3 antibody, EC 2.3.2.27 antibody, RING finger protein 203 antibody, RING-type E3 ubiquitin transferase ZNRF3 antibody, Zinc/RING finger protein 3 antibody
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UniProt
- Q9ULT6
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途径
- WNT signaling
抗原
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