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ZNRF3 抗体 (AA 120-165) (Biotin)

ZNRF3 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1401073
发货至: 中国
  • 抗原 See all ZNRF3 抗体
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    抗原表位
    • 14
    • 5
    • 1
    • 1
    AA 120-165
    适用
    人, 小鼠, 大鼠
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNRF3 antibody is conjugated to Biotin
    应用范围
    • 13
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ZNRF3
    亚型
    IgG
    Top Product
    Discover our top product ZNRF3 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    别名
    ZNRF3 (ZNRF3 产品)
    别名
    BK747E2.3 antibody, RNF203 antibody, AA591877 antibody, BC019575 antibody, Gm1167 antibody, zinc and ring finger 3 antibody, Znrf3 antibody, ZNRF3 antibody
    背景

    Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133

    Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

    基因ID
    84133
    UniProt
    Q9ULT6
    途径
    WNT signaling
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