DKK1 抗体 (AA 33-266)
Quick Overview for DKK1 抗体 (AA 33-266) (ABIN7149878)
抗原
See all DKK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 33-266
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Dickkopf-related protein 1 protein (33-266AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- DKK1 (Dickkopf Homolog 1 (DKK1))
-
别名
- DKK1
-
背景
-
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Aliases: Dickkopf 1 antibody, Dickkopf 1 homolog antibody, Dickkopf 1 like antibody, Dickkopf homolog 1 antibody, Dickkopf like protein 1 antibody, Dickkopf related protein 1 antibody, Dickkopf WNT signaling pathway inhibitor 1 antibody, Dickkopf-1 antibody, Dickkopf-related protein 1 antibody, DKK 1 antibody, Dkk-1 antibody, Dkk1 antibody, DKK1_HUMAN antibody, hDkk 1 antibody, hDkk-1 antibody, SK antibody
-
UniProt
- O94907
-
途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
-